Europace Advance Access published online on November 11, 2008
Europace, doi:10.1093/europace/eun301
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TECHNICAL ISSUES
Performance and survival of transvenous defibrillation leads: need for a European data registry
1 Division of Cardiology, University Hospital Magdeburg, Magdeburg, Germany; 2 Cardiovasular Department, Ospedali Riunti di Bergamo, Italy; 3 Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands; 4 Cardiovascular Center, OLV Hospital, Aalst, Belgium; 5 Cardiac Pacing and Rhythmology Department, Le Chesnay, France; 6 Cardiac Arrhythmia and Electrophysiology Research Unit, Hospital General Universitario La Paz, Madrid, Spain; 7 Wessex Cardiothoracic Centre, Southampton University Hospitals NHS Trust, Southampton, Hampshire, UK
Although the use of implantable cardioverter defibrillator (ICD) therapy has increased over the last decades, the reporting of ICD lead performance is inadequate. So far, there is neither a European nor worldwide registry on ICD leads. The published long-term results from national or multicentre registries encompass relatively small patient cohorts. Nevertheless, the failure of ICD leads may have substantial clinical consequences, including failure to sense, failure to pace, failure to defibrillate, inappropriate shocks, and even death of the patient. The reported ICD lead survival varies significantly between studies: 91–99% at 2 years, 85–95% at 5 years, and 60–72% at 8 years. Thus, the true incidence of lead malfunction cannot be defined as outlined in the present review. One current initiative of the European Heart Rhythm Association is to initiate and develop a Europe-wide registry to monitor, over a prolonged follow-up period, the performance of ICDs and ICD leads.
Key Words: Defibrillator, Lead, Failure, Inappropriate shocks, Registry
* Corresponding author. Tel: +44 0 23 80 796240. E-mail address: jmm{at}hrclinic.org
Manuscript submitted 26 September 2008. Accepted after revision 8 October 2008.
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