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Europace 2004 6(2):130-133; doi:10.1016/j.eupc.2003.11.009
© 2004 by European Society of Cardiology
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CASE REPORT

Electrical storm in Brugada syndrome successfully treated using isoprenaline

P. Maurya,*, P. Couderca, M. Delaya, S. Bovedab and J. Brugadac

aFederation of Cardiology, University Hospital Rangueil 31059 Toulouse Cedex 09, France; bClinique Pasteur Toulouse, France; cCardiovascular Institute, Hospital Clinic Barcelona, Spain

A case of an electrical storm occurring in a patient implanted with a cardioverter-defibrillator for Brugada syndrome is reported. Recurrent ventricular fibrillation was initiated by short-coupled isolated monomorphic ventricular premature beats probably originating from the right ventricular outflow tract, associated with a manifest electrocardiographic pattern of Brugada syndrome. Infusion of atropine accelerated the heart rate but did not prevent ventricular fibrillation, however, low doses of isoprenaline quickly obviated any recurrence of ventricular fibrillation. This was associated with the disappearance of the short-coupled premature beats together with a normalization of the electrocardiographic pattern. Possible mechanisms are discussed according to the accepted pathophysiological hypothesis.

Key Words: electrical storm, Brugada syndrome, isoprenaline

*Corresponding author. Tel.: +33-5-61-32-20-94; fax: +33-5-61-32-22-46. E-mail address: mauryjphil{at}hotmail.com (P. Maury).


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