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Europace Advance Access originally published online on December 18, 2008
Europace 2009 11(3):376-378; doi:10.1093/europace/eun336
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org


SHORT COMMUNICATIONS

Long-QT syndrome and torsades de pointes in a patient with Takotsubo cardiomyopathy: an unusual case

Saagar Mahida1,*, Chrysoula Dalageorgou2 and Elijah R. Behr1

1 Department of Cardiology, St George's Hospital, Blackshaw Road, London, UK; 2 Department of Child Health, St George's Hospital, Blackshaw Road, London, UK

Takotsubo cardiomyopathy is a syndrome characterized by transient left ventricular apical ballooning associated with electrocardiogram (ECG) changes and minimal myocardial enzymatic release, mimicking acute myocardial infarction in patients without significant coronary disease at angiography. We report an unusual case of a patient who presented with Takotsubo cardiomyopathy associated with long-QT syndrome and who developed cardiac arrest secondary to torsades de pointes.The relationship between Takotsubo cardiomyopathy and abnormal repolarization has been well documented. Despite this, there have been few reports of malignant ventricular arrhythmias or sudden death. This report suggests that prolongation of QTc interval in Takotsubo cardiomyopathy may not be as benign as previously suggested but may in fact uncover an abnormality of repolarization that may be genetic in basis and carry a risk of sudden death.


* Corresponding author. Tel: +44 7966965632. Email: saagar7m7{at}yahoo.co.uk

Manuscript submitted 3 November 2008. Accepted after revision 12 November 2008.


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E. R. Behr and S. Mahida
Takotsubo cardiomyopathy and the long-QT syndrome: an insult to repolarization reserve
Europace, June 1, 2009; 11(6): 697 - 700.
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