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Europace 2001 3(2):100-107; doi:10.1053/eupc.2001.0150
© 2001 by European Society of Cardiology
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REGULAR ARTICLES

Further evidence of localized posterior interatrial conduction delay in lone paroxysmal atrial fibrillation

P. G. Platonov1, S. Yuan2, E. Hertervig2, O. Kongstad2, A. Roijer2, A. B. Vygovsky1, L. V. Chireikin1 and S. B. Olsson2

1Arrhythmia Research Laboratory, Research Institute of Cardiology St Petersburg, Russia; 2Department of Cardiology, Lund University Sweden

AIMS: Prolongation of interatrial conduction time has been reported in patients with paroxysmal atrial fibrillation (PAF). The study objective was to localize the region of the conduction delay in patients with lone PAF.

METHODS AND RESULTS: Twenty-one patients with lone PAF and 23 patients with AV nodal re-entrant tachycardia ablation without history of PAF (control group) were recruited. Endocardial recordings were made during sinus rhythm and programmed atrial stimulation. The authors measured the interatrial conduction time, the ‘right-sided’ conduction time between the high lateral right atrium and the proximal coronary sinus (RA-CSp), and the ‘left-sided’ conduction time between the proximal and the distal coronary sinus (CSp-LA). During sinus rhythm, the interatrial conduction time was longer in the PAF group (103±19 vs 86±12 ms, P<0·01) due to delay of right-sided conduction (RA-CSp was 74±20 vs 56±10 ms, P<0·01). During programmed stimulation at the distal coronary sinus, the maximal RA-CSp time was also longer in the PAF group (110±47 vs 69±16 ms,P<0·05). No differences in CSp-LA time were observed.

CONCLUSION: This study supports the role of posterior septal right atrial conduction disturbances in the genesis of lone PAF.

Key Words: Lone atrial fibrillation, interatrial conduction, electrophysiology

Correspondence: Pyotr G. Platonov, MD, Department of Cardiology, University Hospital, SE-221 85 Lund, Sweden. E-mail: ppg{at}cpr.spb.ru

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