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Europace 2005 7(6):535-536; doi:10.1016/j.eupc.2005.06.002
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© 2005 The European Society of Cardiology. Published by Elsevier Ltd. All rights reserved.

One heart, two minds

Ernest W. Lau* and David H. Birnie 1

University of Ottawa Heart Institute 40 Ruskin Street, Ottawa, Ontario K1Y 4W7, Canada

Manuscript submitted 29 September 2004. Accepted after revision 20 June 2005.

*Corresponding author. Queen Elizabeth Hospital, Cardiology, Edgbaston, Birmingham, West Midlands B15 2TH, United Kingdom. Tel.: +44 121 472 1311. E-mail address: ernest.lau{at}btinternet.com


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A case of complex atrial tachyarrhythmias following orthotopic heart transplantation is presented. The ablation strategy in such a situation and the outcome achieved are discussed.

Key Words: cardiac transplantation, atrial flutter, atrial tachycardia, ablation, suture line

Conduction of the native sinus rhythm across the suture line to the donor heart occurs in up to 10% of patients following orthotopic cardiac transplantation. Conduction of atrial arrhythmias occurs less frequently. We describe a complex case of atrial tachyarrhythmias involving the interaction between the native right atrium (NRA) and donor right atrium (DRA) across the suture line.

A 23-year-old man underwent cardiac transplantation at the age of 17 after viral myocarditis. Five years after transplantation, he developed two morphologically distinct forms of atrial flutter/tachycardia. At electrophysiological study, the NRA was in atrial tachycardia with a cycle length of 245 ms and dissociated from the DRA, which was in typical counter-clockwise atrial flutter with a cycle length of 300 ms, as judged by the activation sequence recorded on a halo catheter positioned around the tricuspid annulus of the donor heart and entrainment from the cavo-tricuspid isthmus (Fig. 1(a)). After successful cavo-tricuspid isthmus ablation (Fig. 2), the atrial tachycardia in the NRA began conducting 2:1 to the DRA and ventricles (Fig. 1(b)). Activation covered less than 50% of the tachycardia cycle length in the NRA, and ablation of the earliest site in the antero-superior region of the NRA terminated the tachycardia (Fig. 2). Afterwards, the rhythm alternated between sinus rhythm from the DRA capturing both the NRA and ventricles (Fig. 1(c)) and sinus rhythm from the NRA capturing both the DRA and ventricles (Fig. 1(d)). To prevent any recurrent atrial tachycardia in the NRA being conducted to the donor heart, after verifying that the donor sinus node was chronotropically competent, the conduction point between the NRA and DRA was also ablated (Fig. 2). Afterwards, the patient remained in sinus rhythm from the DRA with dissociated P waves from the NRA, also visible on the electrocardiogram. This case illustrates the exhaustive ablation strategy that may have to be employed in such a case.



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Figure 1 Electrograms recorded during different forms of interaction between the native and donor right atria. NRA: native right atrial signal; DRA: donor right atrial signal; H: His bundle potential; V: local ventricular electrogram recorded by the His bundle catheter.

 



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Figure 2 Schematic diagram of the right heart in conventional Lower and Shumway[1]Go orthotopic cardiac transplantation and the ablation strategy used to treat the associated arrhythmias in this case. With the Lower and Shumway technique, the donor right atrium (DRA) is incised between the superior vena cava (SVC) and inferior vena cava (IVC) and joined to a cuff of the native right atrium (NRA) including the SVC and IVC but not the appendage. Thus the patient ends up with two sino-atrial nodes (SANs) (and occasionally two independent P waves on the electrocardiogram). Ablation (marked with Xs) was performed across the cavo-tricuspid isthmus of the donor heart from the tricuspid annulus (TA) to the inter-atrial anastomosis line. Next, ablation of the earliest activation site terminated the NRA atrial tachycardia (AT*). Finally, the conduction point across the inter-atrial anastomosis suture line was also ablated, electrically isolating the NRA and DRA.

 

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1Tel.: +1 613 761 4914; fax: +1 613 761 4407. dbirnie{at}ottawaheart.ca Back


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[1] Aziz T.M., Burgess M.I., El Gamel A., Campbell C.S., Rahman A.N., Deiraniya A.K., et al. Orthotopic cardiac transplantation technique: a survey of current practice. Ann Thorac Surg 1999; 68: 1242–1246.[Abstract/Free Full Text]


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This Article
Right arrow Abstract Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
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