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Europace 2002 4(2):137-141; doi:10.1053/eupc.2002.0218
© 2002 by European Society of Cardiology
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REGULAR ARTICLES

Pre-implant determinants of adequate long-term function of single lead VDD pacemakers

S. Pakarinen and L. Toivonen

Cardiovascular Laboratory, Division of Cardiology, Helsinki University Central Hospital Helsinki, Finland

Manuscript submitted 20 March 2001. Accepted after revision 13 January 2002.

Correspondence: Sami Pakarinen, MD, Division of Cardiology, Helsinki University Central Hospital, P.O. Box 340, Haartmaninkatu 4, FI-00290 Helsinki, Finland. E-mail: sami.pakarinen{at}hus.fi

Key Words: Single lead VDD pacing, heart block, atrioventricular block, sinus node dysfunction, atrial fibrillation, prediction


    Aims
 Top
 Aims
 Methods and results
 Conclusions
 References
 
An inherent limitation of single lead VDD pacing is the inability to stimulate the atria. Reprogramming and upgrading the pacemaker system may be required when sinus node dysfunction, atrial undersensing, or atrial fibrillation develop. We evaluated whether routine clinical information is sufficient to select patients to benefit in long-term from VDD pacing.


    Methods and results
 Top
 Aims
 Methods and results
 Conclusions
 References
 
We collected data on 12-lead and monitored electrocardiograms and routine clinical information at implantation of a VDD pacing system in 350 consecutive patients with grade II or III atrioventricular conduction block. The age at implantation was 74·5±8·0 years, and the follow-up lasted 1·5±1·5 years. The cumulative maintenance of VDD pacing mode was 91·4%. Loss of VDD mode was due to permanent atrial fibrillation in 16 (4·6%), sinus node dysfunction in six (1·7%), atrial undersensing in 11 (3·1%). Chronic atrial fibrillation developed in 23% of patients who had heart enlargement in chest x-ray and a history of paroxysmal atrial fibrillation or flutter. A criterion of normal sinus rate at implantation sufficiently predicted adequate sinus node function. Poor atrial sensing was not predicted by pre-implant characteristics.


    Conclusions
 Top
 Aims
 Methods and results
 Conclusions
 References
 
According to our data, adequate sinus-driven atrial rate and no history of paroxysmal atrial fibrillation and cardiac enlargement predict maintenance of the VDD pacing mode in elderly patients treated for heart block. Routine information available at implantation is sufficient to guide acceptance of single lead VDD pacing therapy.Copyright 2002 The European Society of Cardiology. Published by Elsevier Science Ltd. All rights reserved .


    References
 Top
 Aims
 Methods and results
 Conclusions
 References
 
[1] Nowak B, Voigtlander T, Himmrich E, et al. Cardiac output in single lead VDD pacing versus rate-matched VVIR pacing. Am J Cardiol 1995; 75: 904–907.[CrossRef][Web of Science][Medline]

[2] Rediker DE, Eagle KA, Homma S, et al. Clinical and hemodynamic comparison of VVI versus DDD pacing in patients with DDD pacemakers. Am J Cardiol 1988; 61: 323–329.[CrossRef][Web of Science][Medline]

[3] Menozzi C, Brignole M, Morrachini PV, et al. Intrapatient comparison between chronic VVIR and DDD pacing in patients affected by high degree AV block without heart failure. Pacing Clin Electrophysiol 1990; 13: 1816–1822.[Medline]

[4] Connolly SJ, Kerr CR, Gent M, et al. Effects of physiologic pacing versus ventricular pacing on the risk of strike and death due to cardiovascular causes. N Engl J Med 2000; 342: 1385–1391.[Abstract/Free Full Text]

[5] Wiegand UKH, Bode F, Schneider R, et al. Atrial sensing and AV synchrony in single lead VDD pacemakers: a comparison to DDD devices with bipolar atrial leads. J Cardiovascular Electrophysiol 1999; 10: 513–520.[Web of Science][Medline]

[6] Wiegand UKH, Potratz J, Bode F, et al. Cost-effectiveness of dual-chamber pacemaker therapy: does single lead VDD pacing reduce treatment costs of atrioventricular block? Eur Heart J 2001; 22: 174–180.[Abstract/Free Full Text]

[7] Sun Z-H, Stjernvall J, Laine P, et al. Extensive variation in the signal amplitude of the atria floating VDD pacing electrode. Pacing Clin Electrophysiol 1998; 21: 1760–1765.[Medline]

[8] Toivonen L and Lommi J. Dependence of atrial sensing function on posture in a single lead atrial triggered ventricular (VDD) pacemaker. Pacing Clin Electrophysiol 1996; 19: 309–313.[CrossRef][Medline]

[9] Chamberlain-Webber R, Barnes E, Papouchado M, et al. Long-term survival of VDD pacing. Pacing Clin Electrophysiol 1998; 21: 2246–2248.[CrossRef][Medline]

[10] Wiegand UKH, Bode F, Schneider R, et al. Development of sinus node disease in patients with AV block: implications for single lead VDD pacing. Heart 1999; 81: 580–585.[Abstract/Free Full Text]

[11] Nowak B, Voigtlander T, Rosocha S, et al. Paroxysmal atrial fibrillation and high degree AV block: use of single lead VDDR pacing with mode switching. Pacing Clin Electrophysiol 1998; 21: 1927–1933.[Medline]

[12] Papouchado M and Pitts Crick JC. Evolution of atrial signals from single lead VDD pacemaker. Pacing Clin Electrophysiol 1996; 19: 1772–1776.[Medline]

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[14] De Cock CC, Van Campen LCMC, Huygens J, Kamp O, Visser CA. Usefulness of echocardiography to predict inappropriate atrial sensing in single lead VDD pacing. Pacing Clin Electrophysiol 1999; 22: 1344–1347.[Medline]


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