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Europace Advance Access published online on November 9, 2009

Europace, doi:10.1093/europace/eup359
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org.


CASE REPORT

Intrinsic neural reflexes in the post-transplant human heart

Krishnakumar Nair, Menashe Waxman, Talha Farid and Kumaraswamy Nanthakumar*

Division of Cardiology, University Health Network, Toronto General Hospital, 150 Gerrard Street West, GW 3-522, Toronto, ON, Canada M5G 2C4

Radiofrequency ablation of post-transplant flutter in a centrally denervated donor atrium at a site remote from the AV node resulted in transient worsening of AV nodal conduction, with absent central vagal reinnervation. This could be an electrophysiological marker of intact innervation to the donor AV node from the intrinsic cardiac neuronal plexus, not demonstrated in human hearts earlier.

Key Words: Cardiac transplant, Flutter, Reinnervation, Cardiac plexus, Ablation


* Corresponding author. Tel: +1 416 340 4442, Fax: +1 416 340 4457, Email: k.nanthakumar{at}uhn.on.ca

Manuscript submitted 15 September 2009. Accepted after revision 15 October 2009.


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