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Europace Advance Access published online on November 12, 2008
Europace, doi:10.1093/europace/eun315
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

CLINICAL RESEARCH

Obstructive sleep apnoea risk profile and the risk of recurrence of atrial fibrillation after catheter ablation

Ri-Bo Tang1, Jian-Zeng Dong1, Xing-Peng Liu1, Jun-Ping Kang1, Shao-Fang Ding2, Li Wang2, De-Yong Long1, Rong-Hui Yu1, Xiao-Hui Liu1, Shuang Liu2 and Chang-Sheng Ma1,*

1 Department of Cardiology, Beijing An Zhen Hospital, Capital Medical University, Chaoyang District, Beijing 100029, People's Republic of China; 2 Department of Respiratory Medicine, Beijing An Zhen Hospital, Capital Medical University, Beijing, People's Republic of China

Aims: The aim of this study was to identify the impact of obstructive sleep apnoea (OSA) on recurrence after catheter ablation of paroxysmal atrial fibrillation (AF).

Methods and results: One hundred and seventy-eight consecutive patients with paroxysmal AF who underwent index circumferential pulmonary vein (PV) isolation were prospectively enrolled. The patients were divided into high risk (HR group) and low risk (LR group) for OSA group with Berlin questionnaire. Of the 178 patients, 104 (58.4%) were in the HR group and 74 (41.6%) were in the LR group. After a mean follow-up of 344 ± 137 (91–572) days, 44 patients (24.7%) experienced recurrence, and the recurrence rate did not differ between the HR (25.0%) and LR groups (24.3%, P = 0.855). Cox analysis revealed that PV isolation was the only independent predictor of recurrence (hazard ratio 5.11, 95% confidence interval 1.42–18.47, P = 0.013). There was no significant difference in the incidence of complications between the HR and LR groups (2.9 vs. 1.9%, P = 0.729).

Conclusion: The recurrence rate and incidence of complications did not differ in patients with different risk profiles for OSA. The presence of OSA should not lower the decision threshold to choose an ablative procedure in paroxysmal AF.

Key Words: Atrial fibrillation, Catheter ablation, Obstructive sleep apnoea, Recurrence

* Corresponding author. Tel: +86 10 64456412, Fax: +86 10 64456078, Email: chshma{at}vip.sina.com

Manuscript submitted 16 August 2008. Accepted after revision 27 October 2008.


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