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Europace Advance Access published online on June 16, 2008
Europace, doi:10.1093/europace/eun150
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

Primary prevention of sudden cardiac death using implantable cardioverter defibrillators

Ligang Ding, Wei Hua*, Hongxia Niu, Keping Chen and Shu Zhang

Center of Arrhythmia, Fuwai Cardiovascular Hospital, Peking Union Medical College, Beijing, China

Despite substantial advances in prevention and treatment of cardiovascular diseases, sudden cardiac death (SCD) remains a leading cause of death in industrialized countries. Implantable cardioverter defibrillator (ICD) has been demonstrated to be an attractive option for primary prevention of SCD in high-risk patients. This review discusses the progress in the risk stratification for selecting high-risk patients, highlights the clinical trials of primary prevention for SCD, outlines the efficacy of combined use of cardiac resynchronization therapy with ICD, and analyses the cost-effectiveness issue of this device.

Key Words: Sudden cardiac death, Implantable cardioverter defibrillator, Primary prevention

* Corresponding author. Tel/fax: +86 1088398290. E-mail address: drhua{at}vip.sina.com

Manuscript submitted 16 December 2007. Accepted after revision 19 May 2008.


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