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Europace 2006 8(12):1051-1053; doi:10.1093/europace/eul118
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© The European Society of Cardiology 2006. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

ELECTROPHYSIOLOGY

Torsade de pointes induced by short-term oral amiodarone therapy

Hong Euy Lim*, Hui-Nam Pak, Jeong Cheon Ahn, Woo Hyuk Song and Young-Hoon Kim

Division of Cardiology, Korea University Cardiovascular Center, Ansan Hospital, 516 Gojan-1-Dong, Danwon-ku, Ansan 425-707, Republic of Korea

Although amiodarone appears to have few pro-arrhythmic effects, torsade de pointes (TdP) has been observed during long-term drug administration, usually in conjunction with electrolyte disturbances, a change in drug dosage, or concomitant drug therapy. We report two cases of amiodarone-induced TdP shortly after administration of a low dose of oral amiodarone, in the absence of predisposing factors.

Key Words: Amiodarone, Torsade de pointes, QT prolongation

* Corresponding author. Tel: +82 31 412 6565; fax: +82 31 412 5594. E-mail address: hongeuy{at}korea.ac.kr


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