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Europace Advance Access originally published online on November 10, 2006
Europace 2006 8(12):1045-1047; doi:10.1093/europace/eul121
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© The European Society of Cardiology 2006. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

ELECTROPHYSIOLOGY

Electrophysiological study in a patient with Fabry disease and a short PQ interval

Marek Jastrzebski1,*, Bogumila Bacior1, Pawel Petkow Dimitrow2 and Kalina Kawecka-Jaszcz1

1 I Cardiac Department, Jagiellonian University College of Medicine, ul. Kopernika 17, 31-501 Krakow, Poland; 2 II Cardiac Department, Jagiellonian University College of Medicine, Krakow, Poland

A short PQ interval is a common finding in patients with Fabry disease. However, there have been few electrophysiological studies in Fabry disease, and it is not clear whether the short PQ interval that is present in this disease results from preexcitation or enhanced atrioventricular nodal conduction. We present a case of a 43-year-old man with syncope, sick sinus syndrome, a PQ interval of 80 ms, and palpitations. Electrophysiological study showed PA, AH, and HV intervals of 24, 32, and 34 ms, respectively, and features of enhanced atrioventricular nodal conduction. The presence of an atrioventricular accessory pathway was excluded. We conclude that the short PQ interval in Fabry disease can result from accelerated conduction in the atrioventricular node.

Key Words: Fabry disease, WPW syndrome, Atrioventricular node, Left ventricular hypertrophy, Cardiomyopathy, Enhanced atrioventricular nodal conduction

* Corresponding author. Tel: +048 124247301048 124247322; Fax: , +048 124247320. E-mail address: mcjastrz{at}cyf-kr.edu.pl


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