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Europace 2006 8(1):37-41; doi:10.1093/europace/euj016
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© The European Society of Cardiology 2006. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

ELECTROPHYSIOLOGY

Volume measurement by CARTOTM compared with cardiac magnetic resonance

F. Grothues1,*, O. Wolfram1, C. Fantoni1, H. Boenigk1, A. Götte1, C. Tempelmann2, H.U. Klein1 and A. Auricchio1

Department of Cardiology, Otto-von-Guericke-University Leipziger Strasse 44, D-39120 Magdeburg Germany ; Department of Neurology II, Otto-von-Guericke-University Leipziger Strasse 44, D-39120 Magdeburg Germany

Aims The CARTOTM electrophysiological mapping system has demonstrated accurate results for end-diastolic ventricular volumes in casts and animals. However, in humans, a comparison with cardiac magnetic resonance (CMR), the non-invasive gold standard for volumetric analysis, has not yet been performed.

Methods and results A total of 34 (29 male) heart failure patients (NYHA class III/IV) underwent an electrophysiological mapping procedure with the CARTO system in the left ventricle (LV) (n=34) and right ventricle (RV) (n=12) and CMR for RV and LV end-diastolic volume (RVEDV and LVEDV) measurements another day. Mean LVEDV was comparable between CMR and CARTO (328±95 and 320±92 mL, respectively; P=NS), whereas RV volumes measured by CARTO were larger (CMR 140±48 vs. CARTO 176±47 mL; P<0.01). Overall, we found a good correlation between CMR and CARTO measurements for both chambers; however, the Bland–Altman analysis showed a non-interchangeability of these methods. Measurement differences were independent of chamber size, but significantly affected by the number of acquired mapping points.

Conclusion Although CMR and CARTO showed a good correlation in the measurement of RVEDV and LVEDV in a group of heart failure patients, the clinical interchangeability of the two methods may be questioned.

Key Words: Electroanatomical mapping, Cardiac magnetic resonance, Volumetric analysis, Left ventricle, Right ventricle, Heart failure

Corresponding author. Tel: +49 391 6713203; fax: +49 391 6713284. E-mail address: frank.grothues{at}medizin.uni-magdeburg.de


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