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Europace 2005 7(5):492-499; doi:10.1016/j.eupc.2005.05.012
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© 2005 The European Society of Cardiology. Published by Elsevier Ltd. All rights reserved.


REVIEW ARTICLE

Anticoagulation in atrial fibrillation and flutter

M. F. Scholtena,*, A. S. Thorntona, J. M. Mekela, P. J. Koudstaalb and L. J. Jordaensa

aDepartment of Clinical Electrophysiology, Thoraxcentre, Erasmus University Medical Centre Dr Molewaterplein 40, 3015 GM, Rotterdam, The Netherlands; bDepartment of Neurology, Erasmus University Medical Centre Dr Molewaterplein 40, 3015 GM, Rotterdam, The Netherlands

Atrial fibrillation and atrial flutter are important risk factors for stroke. Based on a literature search, pathogenesis of thromboembolism, risk assessment in patients, efficacy of anticoagulation therapy and its alternatives are discussed. Special emphasis is put on issues like paroxysmal atrial fibrillation, atrial flutter and anticoagulation surrounding catheter ablation and cardioversion. A strategy for anticoagulation around the time of pulmonary vein ablation is suggested.

Key Words: atrial fibrillation, anticoagulation, catheterablation


*Corresponding author. Tel.: +31 10 463 3991; fax: +31 10 463 4420. E-mail address: m.f.scholten{at}erasmusmc.nl (M.F. Scholten)


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