Skip Navigation

Europace 2002 4(3):303-310; doi:10.1053/eupc.2002.0246
© 2002 by European Society of Cardiology
This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Schreier, G.
Right arrow Articles by Tscheliessnigg, K.-H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Schreier, G.
Right arrow Articles by Tscheliessnigg, K.-H.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

REGULAR ARTICLES

Correlation between changes in stroke volume and the paced intracardiac electrogram

G. Schreier1, P. Kastner1, S. Schaffellner2, B. Grasser2, F. Iberer2 and K.-H. Tscheliessnigg2

1ARC Seibersdorf research GmbH, Graz Office, Grottenhofstraße 3, A-8053, Graz, Austria ; 2Division of Surgery, Department of Transplantation, University of Graz Auenbruggerplatz 29, A-8036, Graz, Austria

AIM: The aim of this study was to examine the relation between cardiac haemodynamics and parameters extracted from the intracardiac electrogram obtained during pacing, i.e. ventricular evoked response.

METHODS AND RESULTS: In the course of routinely scheduled right heart catheterization, intracardiac electrograms and cardiac haemodynamics were monitored simultaneously in ten heart transplant patients (two females, aged 48±12 (18–59) years), using pacemaker telemetry and Swan–Ganz thermodilution techniques. Different haemodynamic states were induced by pacemaker programming (pacing rate changes) and table tilting (postural changes).

Forty different haemodynamic states were assessed, with an average of three (2–4) haemodynamic variations in each patient. Linear regression analysis between relative stroke volume changes and relative changes in the R wave slew rate as extracted from the evoked responses revealed a strong, inverse, and highly significant correlation (r=–0·93, P< 0·0001) between those parameters. Similar results were obtained for pacing rate and postural variations alone, respectively.

CONCLUSIONS: The strong correlation between changes in stroke volume and R slew rate indicates that paced intracardiac electrograms reflect changes in the size and geometry of the heart. Telemetrically recorded intracardiac electrograms may thus be used non-invasively to assess key aspects of cardiac haemodynamics. Copyright 2002 The European Society of Cardiology. Published by Elsevier Science Ltd. All rights reserved.

Key Words: Intracardiac electrogram, electrophysiology, haemodynamics, pacemaker, ventricular evoked response

Correspondence: Dr Günter Schreier, ARC Seibersdorf research GmbH, Graz Office, Grottenhofstraße 3, A-8053 Graz, Austria. Tel: +43 (316) 265 156; Fax: +43 (316) 265 155. E-mail: guenter.schreier{at}arcs.ac.at


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.