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Europace 2001 3(4):311-316; doi:10.1053/eupc.2001.0182
© 2001 by European Society of Cardiology
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SYNCOPE

Psychiatric conditions in patients with recurrent unexplained syncope

R. Ventura, R. Maas, R. Rüppel, U. Stuhr1, A. Schuchert, T. Meinertz and C. A. Nienaber

Department of Cardiology, University Hospital Eppendorf Hamburg, Germany; 1Department of Psychosomatic Medicine, University Hospital Eppendorf Hamburg, Germany

Abstract

AIMS: The relationship between syncope and psychiatric disorders is little investigated. This study evaluated the prevalence of psychiatric diseases and prognostic outcome in patients with recurrent unexplained syncope.

METHODS AND RESULTS: After an inconclusive standard diagnostic work-up for syncope, including head-up tilt testing, a psychiatric evaluation was offered to 50 consecutive patients with recurrent syncope. The evaluation was accepted by 26 patients (77% females, 36±16 years) and refused by 24 (63% females, 50±19 years). A psychiatric disorder was diagnosed in 21 (81%) patients: 12 had depression, four panic attacks, two general anxiety, and three a somatization disorder. Only five patients showed normal psychosocial function. Of the patients with psychiatric disorders four accepted psychiatric care, such as psychotherapy and/or pharmacotherapy; 17 patients refused treatment. During 6 months of follow-up no patient under psychiatric care had syncope, while all patients without psycho- or pharmacotherapy had recurrent syncopal events. In these patients the median of syncopal episodes was three in a 6 months interval before and after clinical assessment. Patients who refused both psychiatric evaluation and therapy continued to experience syncope as before.

CONCLUSIONS: In patients with recurrent unexplained syncope psychiatric alteration is common. However, patients seldom accepted a psychiatric evaluation and treatment.

Key Words: Recurrent unexplained syncope, psychiatric diseases


Correspondence: Rodolfo Ventura, MD, Department of Cardiology, University Hospital Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany. E-mail: ventura{at}uke.uni-hamburg.de


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