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Europace 2009 11(Supplement 5):v87-v92; doi:10.1093/europace/eup305
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org.

This article appears in the following Europace issue: Spotlight Issue: Cardiac Resynchronization Therapy [View the issue table of contents]

Cardiac resynchronization therapy in combination with implantable cardioverter–defibrillator

J. Claude Daubert*, Christophe Leclercq and Philippe Mabo

Department of Cardiology and Vascular Diseases, Hôpital Pontchaillou-CHU, Rennes, 35033 France

Device therapy for heart failure has a spectacular development during the last 10 years. Patients with chronic heart failure might benefit from electrical therapy with a view to: (i) resynchronize the failing and dyssynchronized heart and improve its mechanical performance or (ii) prevent the risk of sudden death by automatic defibrillation. These two therapies can be applied together with a combined device, the biventricular implantable cardioverter-defibrillator (CRT-D). Today, the proportion of CRT-D devices among all CRT devices implanted around the world is more than 75% and more than 85% in the USA. This review article will try to answer some important questions for clinical practice: is the growing use of CRT-D devices supported by clinical evidence? Is the risk-benefit profile of CRT-D favourable in particular in mildly symptomatic patients?

Key Words: Cardiac resynchronisation therapy, Implantable cardioverter defibrillator (ICD), Biventricular ICD, Heart failure

* Corresponding author. Email: jean-claude.daubert{at}chu-rennes.fr


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