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Europace Advance Access originally published online on January 30, 2009
Europace 2009 11(3):385-387; doi:10.1093/europace/eun396
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

SHORT COMMUNICATIONS

Provocation of silence

Jurren M. van Opstal*, Paul G.A. Volders and Harry J.G.M. Crijns

Department of Cardiology, Maastricht University Medical Centre, P. Debyelaan 25, PO Box 5800, 6202 AZ Maastricht, The Netherlands

We describe the development of a Brugada ECG together with sinus- and ventricular arrest after intravenous flecainide for atrial fibrillation in a patient in whom eventually a SCN5a mutation was identified. Unrecognized SCN5A mutations could underlie class IC-induced sinus arrest and conduction defects in some patients.

* Corresponding author. Tel: +31 43 3875093, Fax: +31 43 3875104, Email jmvanopstal{at}yahoo.com

Manuscript submitted 8 December 2008. Accepted after revision 28 December 2008.


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