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Europace Advance Access originally published online on August 4, 2009
Europace 2009 11(10):1396-1398; doi:10.1093/europace/eup211
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org.

SHORT COMMUNICATIONS

Catecholamine challenge unmasking high-risk features in the Wolff–Parkinson–White syndrome

Ryan G. Aleong, Sheldon M. Singh, John R. Levinson and David J. Milan*

Massachusetts General Hospital, Cardiac Arrhythmia Service, GRB 109, 55 Fruit Street, Boston, MA 02114, USA

Risk stratification in patients with Wolff–Parkinson–White (WPW) syndrome is an important clinical problem given a small, but significant risk of sudden death. It has been widely accepted that intermittent pre-excitation is associated with a low-risk pathway. We report a case of WPW with intermittent pre-excitation at baseline, but with marked sensitivity to adrenergic stimulation, revealed by exercise and isoproterenol administration.

* Corresponding author. Tel: +1 617 726 5067, Fax: +1 617 726 3852, Email: dmilan{at}partners.org

Manuscript submitted 4 June 2009. Accepted after revision 8 July 2009.


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