Skip Navigation

Europace 2008 10(Supplement 3):iii96-iii100; doi:10.1093/europace/eun232
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Parthenakis, F. I.
Right arrow Articles by Vardas, P. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Parthenakis, F. I.
Right arrow Articles by Vardas, P. E.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

This article appears in the following Europace issue: Spotlight Issue: Cardiac Imaging in EP and CRT [View the issue table of contents]

IMAGING IN CRT

CRT and exercise capacity in heart failure: the impact of mitral valve regurgitation

Frangiskos I. Parthenakis, Alexandros P. Patrianakos, Emmanuel N. Simantirakis and Panos E. Vardas*

Cardiology Department, Heraklion University Hospital, PO Box 1352, Heraklion, Crete, Greece

Cardiac resynchronization therapy (CRT) has emerged as an established therapy for patients with end-stage heart failure (HF) and symptoms refractory to optimal medication. Resynchronization of the ventricles leads to reduced functional mitral regurgitation (MR) both acutely and chronically and to a better haemodynamic and energetic profile. In addition, large clinical trials have confirmed its beneficial effect on exercise performance and quality of life. The link between the pathophysiological mechanisms of CRT and its positive effect on clinical status has not been fully elucidated. Therefore, this review will focus on the effect of CRT on the haemodynamic role of functional MR and its impact on exercise performance in patients with chronic HF.

Key Words: Cardiac resynchronization, Mitral valve regurgitation, Exercise capacity

* Corresponding author. Tel: +30 2810 392422; fax: +30 2810 542055.E-mail address: cardio{at}med.uoc.gr


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.