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Europace 2008 10(Supplement 3):iii73-iii79; doi:10.1093/europace/eun219
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

This article appears in the following Europace issue: Spotlight Issue: Cardiac Imaging in EP and CRT [View the issue table of contents]

IMAGING IN CRT

Predicting response to CRT. The value of two- and three-dimensional echocardiography

Nina Ajmone Marsan1,*, Ole A. Breithardt2, Victoria Delgado1, Matteo Bertini1 and Laurens F. Tops1

1 Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands; 2 Department of Cardiology, Klinikum Coburg gGmbH, Academic Teaching Hospital of the University of Wuerzburg, Coburg, Germany

Recently, it has been suggested that a direct assessment of left ventricular (LV) mechanical dyssynchrony may improve the selection of candidates to cardiac resynchronization therapy (CRT). In fact, when the established clinical and electrocardiographic selection criteria are applied, response to CRT may vary widely and up to one-third of the patients fail to benefit from CRT. Echocardiography has been extensively applied to assess LV dyssynchrony and to predict favourable response to CRT, using different two- and three-dimensional modalities. In this review, the value of these echocardiographic modalities will be discussed, highlighting the advantages and drawbacks of each technique and evaluating the clinical implications and future perspectives of LV dyssynchrony assessment.

Key Words: Cardiac resynchronization therapy, Left ventricular dyssynchrony, Three-dimensional echocardiography

* Corresponding author. Tel: +31 71 5262020; fax: +31 71 5266809. E-mail address: n.ajmone{at}lumc.nl


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