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Europace 2008 10(3):303-305; doi:10.1093/europace/eun036
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org


ELECTROPHYSIOLOGY

Adenosine can improve the intra-atrial conduction block along the mitral annulus during accessory pathway ablation

Takumi Yamada1,*, Yung R. Lau2, H. Thomas McElderry1, Harish Doppalapudi1 and G. Neal Kay1

1 Division of Cardiovascular Diseases, University of Alabama at Birmingham, VH B147, 1670 University Boulevard, 1530 3rd Avenue South, Birmingham, AL 35294-0019, USA; 2 Department of Pediatric Cardiology, University of Alabama at Birmingham, Birmingham, AL, USA

A 10-year-old boy with a supraventricular tachycardia was referred for catheter ablation. An electrophysiologic study revealed a left lateral concealed accessory pathway (AP). A few radiofrequency (RF) applications targeting the AP resulted in an inadvertent intra-atrial conduction block at the mitral isthmus without any damage to the AP. Adenosine was then administered during left ventricular pacing. Soon after that, the conduction at the mitral isthmus recovered partially, and that change disappeared soon. Those findings suggested that the administration of adenosine may transiently recover the conduction at the mitral isthmus damaged by RF ablation.

Key Words: Adenosine, Accessory pathway, Mitral isthmus, Conduction block, Radiofrequency catheter ablation


* Corresponding author. Tel: +1 205 975 4724; fax: +1 205 975 4720. E-mail address: takumi-y{at}fb4.so-net.ne.jp

Manuscript submitted 10 December 2007. Accepted after revision 21 January 2008.


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