Skip Navigation

Europace 2008 10(2):147-150; doi:10.1093/europace/eum303
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Silvetti, M. S.
Right arrow Articles by Drago, F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Silvetti, M. S.
Right arrow Articles by Drago, F.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

PACING

Circadian pattern of atrial pacing threshold in the young

Massimo S. Silvetti1,*, Antonella De Santis1, Simona Marcora1, Tiziana De Santo2, Nicoletta Grovale2 and Fabrizio Drago1

1 Dipartimento Medico-Chirurgico di Cardiologia, Ospedale Pediatrico Bambino Gesù, Piazza S. Onofrio 4, 00165 Roma, Italy; 2 Medtronic Italy, Italy

Aims: The aim of this study was to evaluate the circadian variation of atrial pacing threshold in young patients.

Methods and results: Atrial Capture ManagementTM (ACM) algorithm is a Medtronic EnPulse pacemaker (PM) feature that uses two algorithms: atrioventricular conduction (AVC) (atrial pacing and spontaneous AVC) and atrial chamber reset (ACR) [intrinsic atrial activity with atrioventricular block (AVB)]. For this prospective, non-randomized study, ACM automatically measured and recorded thresholds every 4 h. Data are reported as median (range) or mean ± SD. In 2004–05, 14 consecutive patients (11 males, 79%), aged 12 years (1 day–24 years) received an EnPulse DDD/R PM for AVB (eight patients, 57%) or sinus node dysfunction. A new pacing system was implanted in eight patients (57%) and a replaced PM in six patients. Epicardial leads were implanted in 10 patients (71%). The follow-up duration is 11 (1–18) months: 9742 threshold measurements were attempted (6328 AVC, 3414 ACR), of which 3797 (39%) were successful (1807 AVC, 29%, 1990 ACR, 58%) in 11 (79%) patients. Three infants had no successful measurements. Measurement success was 42 ± 34% (AVC 27 ± 39%, ACR 41 ± 29%). Higher thresholds were found between 00.00 and 12.00 a.m. and lower between 12.00 and 20.00.

Conclusion: Young patients show a circadian variability of atrial threshold with higher thresholds between 00.00 and 12.00.

Key Words: Cardiac pacing, Paediatric age, Circadian variability, Pacing thresholds

* Corresponding author. Tel: +39 06 68591; fax: +39 06 6859 2257. E-mail address: silvetti{at}opbg.net

Manuscript submitted 19 October 2007. Accepted after revision 20 December 2007.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.